Critical reviewAnnals of Anatomy2026Free article

The mandibular lingula (spine of Spix) in contemporary research

A comprehensive critical review of global morphological variability of the mandibular lingula, showing that shape frequencies, morphometric expectations, and surgical landmark value are strongly influenced by study method, population, and the difference between dry-bone and CBCT approaches.

Mugurel Constantin Rusu · Adela Gabriela Stănescu · Alexia Ioana Stancu · Ilinca Maria Stăncioiu · Irina Elena Stăncioiu
The core message

The lingula is clinically important, but its morphology is too variable for simplistic rules.

The review integrates major studies from 2000–2025 and argues that morphology, bilateral symmetry, and landmark reliability depend on how and where the lingula is studied. Clinical planning should therefore be evidence-based, population-aware, and patient-specific.

11,937+mandibular sides synthesised across 19+ populations from six continents
01 · Scope

Why the lingula matters

The lingula is a key landmark for inferior alveolar nerve block, sagittal split ramus osteotomy, and other mandibular ramus procedures. Its reliability therefore matters directly for oral and maxillofacial practice.

25

Years reviewed

Major studies spanning 2000–2025 were synthesised.

5

Shapes discussed

Triangular, truncated, nodular, assimilated, and bridge/M-shaped morphologies.

4694

Subjects

Meta-analytic morphometric data represented 4694 individuals.

19+

Populations

Evidence spanned at least nineteen populations on six continents.

02 · Shapes

The lingula is morphologically diverse

The review consolidates the main morphotypes discussed in contemporary literature and adds the recently described bridge/M-shaped state to the classical four-shape framework.

Triangularcommon in dry-bone studies
Truncatedshorter superior contour
Nodularoften dominant on CBCT
Assimilatedlow-profile or merged outline
Bridge / M-shapednewly reported variant state
03 · Method bias

Dry-bone and CBCT studies do not tell the same story

A central contribution of the review is methodological: the most frequent lingula shape changes when the literature is split by study type. Pooling these data without caution can therefore distort interpretation.

Dry bone → triangular
39%
CBCT → nodular
50.6%
Important methodological caution: if dry-bone and CBCT studies are merged uncritically, apparent “global” shape frequencies may reflect study design as much as anatomy.
04 · Practical messages

Four clinically useful conclusions

The review translates descriptive anatomy into guidance for mandibular procedures and landmark selection.

01

The internal oblique/mylohyoid ridge is a strong auxiliary landmark

It was highly visible in the reviewed evidence and yielded superior reported success rates when used to guide inferior alveolar nerve block.

02

The antilingula should not be trusted alone

The review critically re-evaluates the antilingula and concludes that it has limited value as a sole landmark, although it may still supplement a broader strategy when posterior safety margins are respected.

03

Bilateral symmetry cannot be assumed

Right–left similarity is not consistent enough for procedural planning. Patient-specific assessment is more defensible than symmetrical assumptions.

04

Protocols should be population-aware

The review explicitly argues for evidence-based, population-specific surgical and anaesthetic protocols rather than universal rules.

05 · Conceptual summary

From descriptive variation to safer use

This scheme condenses the review’s logic from morphology and method bias to procedural consequence.

Lingulacritical ramus landmarkMorphologyfive shapes · population variabilityMethod biasdry bone ≠ CBCT frequenciesAsymmetrydo not assume bilateral identityLandmarksridge useful · antilingula limitedProceduresIANB · SSRO · ramus surgeryGuidancepopulation-aware, patient-specific useSaferplanning
Practical takeaway: the review supports evidence-based, population-aware, and patient-specific protocols rather than blind reliance on traditional descriptive assumptions.
06 · Clinical metrics

Selected values highlighted in the review

These values support the argument that auxiliary landmarks may outperform standard assumptions in practice.

95.7%

Ridge visibility

The internal oblique/mylohyoid ridge emerges as a strong alternative landmark.

97.3%

Reported success

Superior IANB success has been reported when that ridge guides injection.

~85%

Traditional method

Conventional IANB success rates are lower in the comparison cited by the review.